The visual patch-clamp method can accurately assess synaptic transmission by measuring postsynaptic currents of the dorsal horn neurons. 可视膜片钳方法可以准确测量脊髓背角神经元的突触后电流从而研究初级传入突触的传递过程。
And the opening proportion of chemical-gated ion channels on postsynaptic membrane was positively related to the potential of presynaptic membrane. 突触后膜上化学门控离子通道的开放比例与突触前膜电位呈正相关;
Synapses are connections between neurons, biological signals are transferred from the presynaptic membrane by the synaptic transmission to the postsynaptic membrane. 突触是神经元之间的连接部位,生物信号从突触前膜经突触传递到突触后膜。
Moreover, we found that presynaptic but not postsynaptic inactivation of presenilins alters short-term plasticity and synaptic facilitation. 并且我们还发现突触前而非突触后早衰蛋白失活将改变短时突触可塑性及易化。
This study shows that there is some pharmacological difference between Imidacloprid and Dimehypo during their interactions with the postsynaptic acetylcholine receptors. 这些结果说明,吡虫啉、杀虫双和乙酰胆碱受体发生相互作用过程存在差异。
The recordings of postsynaptic currents were performed by using the whole-cell voltage-clamp method. 采用全细胞电压钳记录技术,给予选择性受体阻断剂以分离不同的突触后受体电流。
Their average amplitudes were differentially up-or down-regulated, depending on the precise timing of postsynaptic APs relative to EPSPs. 它们的平均振幅是依赖精确的后突触AP与EPSP时间,相差性的上下控制。
Extraction and identification of postsynaptic density protein from rat brain 大鼠脑内突触后致密物蛋白质的提取及鉴定
D-serine modulates the postsynaptic NMDA receptor responses in the rat visual cortex D-丝氨酸对大鼠视皮层神经元突触后NMDA受体功能的调制作用
At the holding potential of0 mV, spontaneous inhibitory postsynaptic currents ( IPSCs) and dorsal root stimulation-evoked IPSCs were recorded as outward currents. 在钳制电压为0毫伏条件下,记录自发的和背根刺激引起的抑制性突触后电流。
PubMed abstract: Long-term potentiation ( LTP) is an enhancement of synaptic strength that can be produced by pairing of presynaptic activity with postsynaptic depolarization. 《公共医学图书馆摘要》:长期电位化(LTP)以前突触活动联对后突触除极化,增加突触讯号强度。
Neurotransmitter receptors mediate signal transduction at the postsynaptic membrane of synaptic connections between neurons in the nervous system. 大脑中神经元突触间的信号传递是由许多神经递质受体介导的。
The improvement of spinal cord slice preparations and records of postsynaptic currents in lamina ⅱ neurons of spinal cord 脊髓薄片制备方法的改进及其脊髓Ⅱ板层神经元突触后电流的记录
These data suggest a new function for NMDA receptors in the ACC as important postsynaptic receptors involved in synaptic transmission, in particular when cells are firing at high frequencies. 此文直接显示NMDA受体参与前额扣带回的突触传递,并提示NMDA受体在前额扣带回中起着调节神经元兴奋的重要作用。
Training in a forelimb reaching task leads to rapid ( within an hour) formation of postsynaptic dendritic spines on the output pyramidal neurons in the contralateral motor cortex. 这种用前肢踩踏的训练,一个小时内就可以在两侧运动皮层的椎体神经元上形成突触后“树枝状小棘”的结构。
Mining the postsynaptic proteome now gives researchers a strategic entry point, and the rest of us a front row seat to witness neuroscience unravel the complexity of human brain disorders. 对突触后蛋白质组学的研究,给了目前的研究者们一个策略上的新切入点,并让我们得以见证当代神经科学对人类脑部疾病的复杂成因层层解密的过程。
A major challenge in studying the synapse is how to tell what observed effects are due to presynaptic factors and which to postsynaptic ones. 研究突触最大的困难在于如何区辨所观察到的反应是来自突触前或突触后因子所导致。
Postsynaptic dense area and the close relationship between synaptic plasticity are essential for the maintenance of synaptic function properly. 突触后致密区与突触可塑性的关系十分密切,对于维持突触发挥正常功能至关重要。
Maturation of presynaptic transmitter secretion machinery and trafficking of postsynaptic receptors are two critical steps in synaptogenesis and synaptic development of central nervous system ( CNS). 突触前递质释放装置的发育成熟和突触后受体的转运是中枢神经系统突触发育过程中非常重要的两个方面。
Our findings challenge the view that LTP in CA1 involves a presynaptic modification, and suggest instead a simple postsynaptic mechanism for both induction and expression of LTP. 我们的研究挑战以长期电位画在CA1促成前突触的改变,并建议一个简单的以后突触改变结构的诱发与显示的长期电位化。
Effects of TFG on the Late Slow Excitatory Postsynaptic Potential of the Neurons in Inferior Mesenteric Ganglion of Guinea-pig in Vitro; The Research of Bile Metabolism after Cholecystectomy 银杏叶总黄酮对豚鼠肠系膜下神经节细胞ls-EPSP的影响胆囊切除术后豚鼠肠道推进功能及胆汁代谢变化的实验研究
Postsynaptic neurons. After clear sky and calm weather, clouds gathered and a storm burst, and it rained with a very violent shower. 神经突触后的神经元在天睛日暖之后突然乌云密集,大风狂起,暴雨倾盆。
Effects of binocular form deprivation on neuron excitory postsynaptic currents in adult visual cortex 双眼形觉剥夺对成年大鼠视皮层兴奋性突触后电流的影响
The frequency of excitatory postsynaptic potential ( EPSP) was also increased in rat brain neurons exposed to Pys. 此外,Pys可引起兴奋性突触后电位(EPSP)频率的增高。
A stimulus intensity-dependent excitatory postsynaptic potential was evoked by orthodromic stimulation. 顺行电刺激可诱发兴奋性突触后电位,并具有刺激强度依赖性。
Postsynaptic potentials manifested current effect and frequency dependency and their IPSP displayed a prolonged inhibition. 突触后电位表现电流效应和频率依赖性,其IPSP具有长时程的抑制作用。
Glutamate binding to postsynaptic AMPA-type glutamate receptors induces depolarizations that cause neuronal firing. 谷氨酸与突触后的AMPA型谷氨酸受体结合后诱发去极化,导致神经元兴奋。
In the past, study of postsynaptic regulatory mechanism is rare. 以往的研究多侧重于突触前和突触间隙调节机制,而对突触后调节机制研究不多。
These changes include presynaptic neurotransmitter release and postsynaptic receptor signal transduction. 这些变化包括突触前神经递质的释放和突触后受体的信号转导。