Loteprednol etabonate was synthesized through oxidation, acylation, hydrolysis and chloromethylation from the starting material prednisolone. 以泼尼松龙为原料,经氧化、酰化、水解成盐、氯甲基化成酯制得氯替泼诺。
Local injection of prednisolone for the treatment of mild sprain or strain of the acromioclavicular joint can result in satisfactory therapeutic efficacy. 对诊断正确的轻度肩锁关节损伤,采取局部注射强的松龙的方法,可以获得满意的效果。
Objective: To explore the clinical efficacy of curing Knee Osteoarthritis by Sodium Hyaluronate and Prednisolone. 目的探讨玻璃酸钠与强的松龙注射液治疗膝关节骨性关节炎的临床疗效。
Treat chronic hepatitis B infection with lamivudine combined prednisolone 拉米夫定联合强的松龙治疗乙型慢性重型肝炎
To compare the effect of sodium hyaluronate and prednisolone on the trauma treating of articular cartilage of the rabbits'temporomandibular joints. 目的比较局部应用透明质酸钠和醋酸强的松龙对兔颞下颌关节软骨损伤后的治疗效果。
Objective To develop a method for the determination of prednisolone acetate in the compound prednisolone acetate nasal drops. 目的建立复方醋酸泼尼松龙滴鼻液中醋酸泼尼松龙含量测定的简便方法。
Simultaneous determination of Prednisone and Prednisolone in the blood and urine by HPLC HPLC同时测定血液与尿液中的泼尼松和泼尼松龙
Clinical Observation on Prednisolone Acetate Treating for 24 Cases with Subacute Thyroiditis 醋酸泼尼松龙局部注射治疗24例亚急性甲状腺炎的临床观察
The combination of prednisolone and azathioprine has only a minor effect, whereas the addition of ciclosporin attenuates protective antibody responses to influenza vaccination. 泼尼松龙和硫唑嘌呤联合应用的影响较小,而加用环孢素则减弱了针对流行性感冒接种的保护性抗体应答。
Conclusion The results show that prednisolone can be delivered to large intestine by synthesized prednisolone prodrug, which has a potential in treatment of colitis. 结论泼尼松龙前体药物具一定结肠定位性,有可能成为一种具有应用前景的结肠炎治疗药物。
Leflunomide in combination with medium/ low dose of prednisolone in treatment of progressive IgA nephropathy 来氟米特联合中小剂量糖皮质激素治疗进展性IgA肾病的研究
A short course of oral prednisolone is widely used to treat preschool children with wheezing who present to a hospital, but there is conflicting evidence regarding its efficacy in this age group. 治疗前来医院就诊的患有喘鸣的学龄前儿童广泛应用短期口服泼尼松治疗,但是,关于这个年龄组的治疗效果有相反的证据。
Of687 children included in the intent-to-treat analysis, 343 were in the prednisolone group and344 in the placebo group. 最终有687份调查结果,343份是来自泼尼松治疗组,344是来自安慰剂治疗组的。
Conclusion Intracavitary injection of prednisolone treatment of auricular pseudocyst is simple, easy to grasp. 结论囊腔内注入强的松龙治疗耳廓假性囊肿操作简单,容易掌握;
We separately analyzed data from three groups of patients: those who received fluorometholone only; those who were initially given fluorometholone then later switched to prednisolone acetate; and those who received prednisolone acetate only. 我们分别分析了三组病人:仅使用丙酮缩氟氢羟龙组;起初使用丙酮缩氟氢羟龙但转用泼尼松龙组;仅使用泼尼松龙组。
A69-year-old man, who had been receiving prednisolone for11 months for treatment of interstitial pneumonia, was diagnosed with acute myeloid leukemia. 患者男性,69岁,使用泼尼松龙治疗间质性肺炎11个月,诊断为急性髓样白血病。
Determination of the related substances in Prednisolone and its tablet by RP-HPLC RP-HPLC测定泼尼松龙的原料和片剂中有关物质
OBJECTIVE: To investigate reversible metabolic pharmacokinetics of prednisone and prednisolone in plasma and blood nucleated cells in 10 healthy male volunteers. 目的:研究强的松、强的松龙在10名男性健康志愿者血浆及血中有核细胞内的可逆代谢药代动力学。
OBJECTIVE To study the preparation of compound prednisolone nasal drops and control its quality. METHODS colorimetry was applied to determine prednisolone acetate in the nasal drops. 目的:研制复方泼尼松龙滴鼻剂,并对其质量进行控制。方法:采用比色法测定制剂中醋酸泼尼松龙的含量。
Eye drops of 1% prednisolone acetate, 1% atropine, and tropicamide were used. 眼部滴用1%百力特、1%阿托品和复方托品酰胺眼液。
METHODS colorimetry was applied to determine prednisolone acetate in the nasal drops. 方法:采用比色法测定制剂中醋酸泼尼松龙的含量。
Conclusions The solubility and dissolution rate of prednisolone acetate are increased after being included by β-cyclodextrin. 结论醋酸泼尼松龙β-环糊精包合物可明显提高醋酸泼尼松龙的溶解度及溶出速率。
AHA-M2 is the special autoimmune antibody of PBC. The efficacy of prednisolone is better for AIH than PBC. 而血中AMA-M2是PBC特征抗体,强的松龙治疗效果AIH优于PBC。
Three prednisolone acete table formulations and a prednisolone tablet formulation with different dissolution rate in vitro and bioavailability in vivo were designed. 选择了不同厂生产的三种醋酸强的松龙片和一种强的松龙片进行体外溶出速率试验和体内生物利用度测定。
Reversible Metabolic Pharmacokinetics of Prednisone and Prednisolone in Plasma and Blood Nucleated Cells in Healthy Volunteers 健康人体血浆及血中有核细胞内强的松与强的松龙的可逆代谢药代动力学
The effects of intrathecal prednisolone acetate administration on analgesia and c-fos protein expression in spinal cord in rats 鞘内注入醋酸泼尼松龙对大鼠镇痛作用及脊髓c-fos表达的影响
The Effect of Intra-articular Injection of Sodium Hyaluronate and Prednisolone on Rabbits ′ Temporomandibular Joints 透明质酸钠和醋酸强的松龙对兔颞下颌关节影响的扫描电镜研究
The results suggested that the new RNA and protein synthesis may be involved in prednisolone induction of PLAP. 结果提示.强的松龙对PLAP的诱导作用与新的RNA及蛋白质合成有关。