Historically, bioinformatics concerned itself with the analysis of the sequences of genes and their products ( proteins), but the field has since expanded to the management, processing, analysis and visualization of large quantities of data from genomics, proteomics, drug screening and medicinal chemistry. 历史上生物信息学涉及基因序列和其产物蛋白质的分析,但是该领域已经扩展到从基因组学、蛋白组学、药物筛选和药物化学中获得的大量资料的管理、处理、分析和形象化。
In response to these constraints, we have undertaken the design of software to automate annotation and visualization of proteomics data in order to accelerate the pace of research. 作为对这些限制的反应,我们进行了软件的设计以自动注释和可视化蛋白质组数据,以便加快研究的步伐。
Proteomics may be defined as the complete characterization of the full complement of proteins in a biological system. 可把蛋白组学定义为生物系统中所有蛋白质的全部表征。
Using proteomics and biological mass spectrometry as the main research methodologies, our primary research interests are to study proteome changes and signal transduction networking associated with infection and innate immunity. 目前主要研究领域和兴趣:本实验室以蛋白质组学及生物质谱学为主要研究方法,重点研究感染与天然免疫过程中的蛋白组变化以及蛋白质信号传导通路。
The prospects of plant proteomics are discussed. 同时对植物蛋白质组学的发展前景进行了讨论。
Study Progress of Serum Differential Proteomics in Hepatocellular Carcinoma 血清差异蛋白质组学在肝癌研究中的进展
Abstract: This review covers the development of proteomics in pancreatic cancer, including the research strategy, technology, content, and problems. 摘要:综述了目前胰腺癌蛋白质组学的研究策略、方法、内容、存在问题及发展方向。
In this article, we summarized progress in research on proteomics in perinatology. 该文就其在该领域中的研究进展作以综述。
In order to achieve the HPP's goals, large and influential proteomics research groups will be needed. 为实现HPP的目标,非常需要大型和有影响力的研究组。
New ideas and technologies in proteomics would impregnate new activities for the development of BNF. 蛋白质组学新思想、新技术的引入,为固氮研究的发展注入了新的活力。
Application of proteomics technology in search of serum markers of early silicosis 蛋白质组学技术在寻找矽肺早期血清标志物中的应用
The systematic study of proteins and protein networks, that is, proteomics, calls for qualitative and quantitative analysis of proteins and peptides. 蛋白质和蛋白质网络的系统研究,即蛋白质组学,需要蛋白质和多肽的定性和定量分析。
In recent years, proteomics and mass spectrometry technology have developed rapidly, which can be used to find specific disease-related proteins as biomarkers for early diagnosis. 近些年来蛋白质组学和质谱技术迅速发展,可以利用这些技术寻找到与疾病相关的特异性的蛋白质分子作为早期诊断的生物标志物。
This chapter describes some of the basic concepts and current approaches to the analysis of MS and MS/ MS data in proteomics. 这一章描述了一些基本的概念及蛋白质组学中MS和MS/MS数据分析的当前方法。
This interdisciplinary course provides a hands-on approach to students in the topics of bioinformatics and proteomics. 本交叉学科课程为学生提供了生物资讯学和蛋白质体学的实验学习方法。
Proteomics and Its Development in Brucellosis Research 蛋白质组学及其在布鲁氏菌中的研究进展
In this paper, techniques of viral infection proteomics, the progress of changes of host cell proteome induced by virus, and serum differential proteome of host after viral infection were introduced. 本文介绍了病毒感染蛋白质组学研究技术、病毒诱导宿主细胞蛋白质组改变和病毒感染宿主血清差异蛋白质组等方面的研究进展。
In this paper, the source of trans-fatty acids, hazards and corresponding proteomics are reviewed. 本文就反式脂肪酸的来源、危害及蛋白质组学的研究进行综述。
Advances in mass spectrometry-driven proteomics rely on robust bioinformatics tools that enable large-scale data analysis. 质谱驱动的蛋白质组学的进展依赖于使得大规模数据分析成为可能的鲁棒的生物信息学工具。
In recent years, plant proteomics have advanced from a qualitative to an accurate quantitative stage. 植物蛋白质组学近年来正从定性向精确定量蛋白质组学的方向发展。
Furthermore, we demonstrate that peptide identifications obtained from high-throughput proteomics can be integrated on a large scale with the human genome. 而且,我们演示了从高通量蛋白质组技术中获取的肽段标识可以与人类基因组进行大规模集成。
He envisions immediate applications in genomics and proteomics, with the new approach providing several improvements over current techniques. 他预想在基因组学和蛋白质组学的直接应用,运用新的方法来达到对现有技术的多方面的提高。
Highly effective separation of complex peptide mixture is a prerequisite for protein identification with high coverage in proteomics. 复杂肽段混合物的有效分离是高覆盖率地鉴定蛋白质混合物的前提。
The development of new vaccine against MTB has showed some promising results based on proteomics. 通过对结核分枝杆菌致病株抗原的分析,为研制预防结核病的新型疫苗拓展了空间。
Another integral part of proteomics is separation of proteins. 另一个蛋白质组学的组成部分是蛋白质的分离作用。
Nonetheless, a need still exists for new digestion approaches that meet the demands of qualitative and quantitative proteomics. 尽管如此,仍然存在着新蛋白酶解方法的开发空间,以满足蛋白质组学中定性和定量的需求。
As well as genomics, proteomics and metabolomics, scientists are also using chemical genomics, an approach that reverses the standard drug discovery process. 除了基因组学、蛋白质组学和代谢组学,科学家还在使用化学基因组学,这是一种逆转标准的药物发现过程的方法。
Similar approaches are being developed to incorporate information to other types of genomics and proteomics databases. 相似的方法正在开发以合并信息到其他类型的基因组和蛋白质组数据库。
It is thus widely used as an initial step for sequence characterization and annotation, phylogeny, genomics, transcriptomics, and proteomics studies. 因此它被广泛地用作序列描述与注释、系统发生、基因组学、转录组学和蛋白质组学研究的一个起始步骤。
As the development of the Proteomics, the studies of the protein phosphorylation have become more important topic. 随着蛋白质组技术的不断发展,蛋白质磷酸化的研究越来越受到广泛的重视。