Protein tyrosine phosphatase ( PTPase) can dephosphorylate the phosphorylating tyrosine, which have consangnineous correlation with proliferation and differentiation of cell, and the obstacle of proliferation and differentiation is one of the tumor's characteristic. 蛋白酪氨酸磷酸酶(proteintyrosinephosphatase,PTPase)能特异地使细胞内磷酸化的酪氨酸残基去磷酸化,与细胞的增殖分化密切相关,而增殖分化障碍正是肿瘤细胞的特征之一。
The relationship between SHP-1, SHP-2 ( src homology-2 domain containing PTPase) and tumor isn't still clear. And report about relationship between SHP-1, SHP-2 and radiation carcinogenesis aren't found. SHP-1和SHP-2为含SH2域(srchomology-2domain)的PTPase,与肿瘤的关系尚不非常明确,与辐射致癌的关系国内外未见相关报道。