The authors first tested the PPAR agonist rosiglitazone in combination with several different chemotherapeutics against various cancer cell lines. 作者第一次测试PPAR激动剂罗格列酮与不同的化疗药物联合对不同癌细胞株的作用。
Our practice-based findings suggest significant associations of rosiglitazone use with higher cardiovascular and all-cause mortality among hemodialysis patients with diabetes. 我们的实验为基础的研究结果表明口服罗格列酮的糖尿病血液透析患者和较高心血管的和各原因的死亡率具有显著相关。
Efficacy and safety of rosiglitazone maleate in treatment of type 2 diabetes patients with uncontrolled hyperglycemia 马来酸罗格列酮治疗血糖控制未达标的2型糖尿病患者的疗效和安全性
Furthermore, the investigators report, the reduction of risk was on a par with traditional antidiabetic drugs, including rosiglitazone, metformin, acarbose, and ramipril. 研究人员还说,羟基氯喹对糖尿病风险的降低与传统抗糖尿病药相当,后者包括罗格列酮、二甲双胍、阿卡波糖和雷米普利。
As such, the researchers say it is difficult to advocate continued use of rosiglitazone for most patients. 研究者说,照这样看,将很难提倡大部分的患者继续使用罗格列酮。
Objective: To investigate the effects of bromocriptine and rosiglitazone and metformin on insulin resistance metabolism of lipids and oxidative stress in rats with polycystic ovary syndrome ( PCOS). 目的:观察溴隐停、二甲双胍、罗格列酮分别对多囊卵巢综合征(PCOS)大鼠胰岛素抵抗、血脂和氧化应激作用。
Investigation of the Therapeutic Effect and Safety of Rosiglitazone Maleat and Sodium in Type 2 Diabetes Mellitus 马来酸罗格列酮与罗格列酮钠对2型糖尿病疗效及安全性的比较
The vascular lesions in diabetes mellitus rosiglitazone treatment group were less severe than those in diabetes mellitus group. 糖尿病罗格列酮治疗组大鼠血管病变明显轻于糖尿病组;
Effect of Rosiglitazone on the Expression of Adiponectin Receptor 1 in Aortas of Type 2 Diabetic Rats 脂联素受体1在2型糖尿病大鼠大血管病变中的表达及罗格列酮的干预研究
Beginning in1999, rosiglitazone maleate and pioglitazone hydrochloride were approved for use. 从1999年开始,马来酸罗格列酮和盐酸匹格列酮被批准使用。
The Anti-atherosclerosis Study on the Role and Mechanism of Rosiglitazone 罗格列酮抗动脉粥样硬化作用及机理的研究
Influence of Rosiglitazone on B Cells Line NIT-1 Proliferation, Apoptosis and Secretion in High Glucose 罗格列酮对不同浓度葡萄糖条件下小鼠胰岛B细胞株NIT-1增殖、凋亡及功能的影响
Effect of rosiglitazone on aquaporin-1 expression in human peritoneal mesothelial cells and human umbilical vein endothelial cells 罗格列酮对人腹膜间皮细胞和脐静脉内皮细胞水孔蛋白-1的影响
International Diabetes: Do rosiglitazone and pioglitazone have different or similar properties in respect to their cardiovascular profiles? 《国际糖尿病》:罗格列酮和吡格列酮对心血管的影响是否有所差别?二者有何相似性?
Therapeutic effects of rosiglitazone on mesangial proliferative glomerulonephritis in rats 罗格列酮对大鼠系膜增生性肾炎的治疗作用
The comparison study of pioglitazone and rosiglitazone on type 2 diabetes with hyperlipemia 吡格列酮和罗格列酮治疗2型糖尿病高脂血症的临床比较研究
Inhibitory Effect of Rosiglitazone on Proliferation and Migration of Rat Vascular Smooth Muscle Cells in Vitro 罗格列酮抑制体外培养大鼠血管平滑肌细胞的增殖和迁移作用
Protective Effect of Rosiglitazone Sodium on Islet β-cell of STZ Induced Diabetic Rats through JNK Pathway 罗格列酮钠保护STZ糖尿病大鼠胰岛β-细胞及对JNK信号通路的影响研究
Inhibitory Effect of Trichostatin A Combined with Rosiglitazone on Proliferation of Stomach Cancer Cells 曲古抑菌素A与罗格列酮联合应用对胃癌细胞增殖的抑制作用
Effects of rosiglitazone and irbesartan on lipid profile and myocardial adiponectin level in rat model with hypercholesterolemia 罗格列酮和厄贝沙坦对高胆固醇血症大鼠血脂及心肌脂联素的干预作用
Effect of Rosiglitazone Sodium on the Apoptosis of Beta Cells in Rats with Experimental Type 1 Diabetic Mellitus 罗格列酮钠对实验性1型糖尿病大鼠胰岛β细胞凋亡的影响
Effect of rosiglitazone on hydrogen peroxide-induced pig's endothelial cell apoptosis 罗格列酮对过氧化氢诱导内皮细胞凋亡的影响
Effects of Rosiglitazone on Rat Kidney Fibroblasts Cultured in High Glucose 罗格列酮对高糖环境大鼠肾脏成纤维细胞影响
Has some of the bad press and issues with rosiglitazone unfairly affected pioglitazone? 有关罗格列酮的一些负面新闻是否会对吡格列酮有影响?
Conclusion Rosiglitazone has protective effects on vascular structure of rats with diabetes mellitus, and the mechanism may relate to the inhibition of PLA2 expression and reduction of inflammation. 结论罗格列酮对糖尿病大鼠血管结构具有保护作用,其机制可能与抑制外周和局部炎症因子PLA2表达而减轻炎症反应有关。
The Effect of Rosiglitazone and Simvastatin on Atherosclerosis in Cholesterol-fed Rabbits 罗格列酮、辛伐他汀合用对兔动脉粥样硬化形成的影响
Effect of Rosiglitazone on the phenotypic transformation of renal tubular epithelial cells and NADPH oxidase of diabetic rabbits 罗格列酮对糖尿病兔肾小管上皮细胞表型转化与NADPH氧化酶的影响
Effect of Rosiglitazone on the expression of COX-2 protein in non alcoholic fatty liver disease rats 罗格列酮钠对非酒精性脂肪肝大鼠COX-2表达的影响
PPAR γ agonist rosiglitazone alleviates hypoxia/ reoxygenation-induced oxidative stress and apoptosis in rat cardiac myocytes PPARγ激动剂罗格列酮对缺氧/复氧大鼠心肌细胞氧化应激和凋亡的影响
The aim of this meta-analysis of randomized clinical trials is to assess the effect of rosiglitazone on the incidence of cancer. 这项对随机临床试验荟萃分析的目的是评价罗格列酮对肿瘤发生率的影响。