At the same time, rainbow trout is an important worldwide farmed fish. Now salmonid aquaculture vaccines are meanly gram negative bacterins. The protective immunity is usually used with adjuvants while this kind of formulation brings lesions on fish impacting its economic value. 同时,虹鳟是世界上广泛养殖的重要冷水鱼,现在鲑鳟类养殖用的疫苗主要是革兰氏阴性细菌苗,保护性免疫通常是菌苗和佐剂一起使用。