saquinavir

1. OBJECTIVE To develop a HPLC assay for the determination of saquinavir and its related substances.
   目的建立测定沙喹那韦含量与有关物质的高效液相色谱法。
2. Aim To investigate the effect of ketoconazole on the metabolism in vitro and pharmacokinetics of saquinavir.
   目的研究酮康唑对沙奎那韦的体外代谢和药物代谢动力学的影响。
3. Synthesis of saquinavir, an HIV protease inhibitor, was researched via convergence method.
   采用平行-连续法合成了HIV蛋白酶抑制剂沙奎那韦。

noun

1. a weak protease inhibitor (trade name Invirase) used in treating HIV

   Synonym:    Invirase