Effect of scoparone on airway smooth muscle proliferation and PKC-α expression in asthmatic rats 滨蒿内酯对大鼠哮喘模型气道平滑肌增殖及PKC-α蛋白表达的影响
Effect of scoparone on intracellular calcium concentration of guinea pig airway smooth muscle cells in primary culture and subculture 滨蒿内酯对原代和传代培养豚鼠气道平滑肌细胞内钙的影响
Vasodilator Effect of Scoparone on the Isolated Aorta of Rats 滨蒿内酯对离体大鼠主动脉平滑肌作用的研究
Objective: To study the changes of IgE, IL-4 and IFN-y in serum and pulmonary tissue homogenate of asthmatic guinea pigs, search for the relationship between IFN-/ IL-4 and IgE and the effects of Scoparone on them. 目的:研究哮喘豚鼠血清及肺组织匀浆中中IgE、白细胞介素-4(IL-4)和干扰素-γ(IFN-γ)的含量变化、相关性及滨蒿内酯对其的影响。
BACKGROUND: Scoparone, which is a major principle separated from traditional Chinese herbs artemisia scoparia, which possesses actions of immunosuppression, anti inflammation and relaxing bronchial smooth muscle. 背景:滨蒿内酯是传统中药茵陈的主要有效成分之一,具有免疫抑制、消炎和舒张支气管平滑肌的作用。
Study on Anti-asthma Mechanism of Scoparone 滨蒿内酯平喘作用机制的研究
CONCLUSION Scoparone may modulate the balance between IL-4 and INF-y to inhibit the abnormal synthesis of IgE in asthmatic guinea pigs. 结论滨蒿内酯可调节因IL-4及IFN-γ之间失衡而导致的IgE异常合成,从而抑制哮喘的发生。
Determination of Scoparone in Different Parts and Harvest Time of Scoparia and Rational Utilization of Its Resources 不同采收期和不同部位茵陈药材滨蒿内酯的含量测定与资源利用建议
The change of subtype Ryanodine receptor ( RyR) in tracheal smooth muscle cells ( TSMC) from asthmatic cavy and the effect of scoparone on the receptor were studied. 研究哮喘豚鼠气管平滑肌细胞Ryanodine受体亚型的变化及滨蒿内酯对其的影响。
Thus analyzing from monomeric compounds in different idioplasm of C. album, the traditional efficacy for clearing heat and relieving sore throat may be formed by gallic acid and scopoletin and scoparone which confirmed the similarity between efficacy of chinese medicine theory with target theory in modern pharmacology. 因此青果不同种质从所含单体化合物角度分析,青果清热利咽的功效可能由没食子酸、东莨菪内酯、滨蒿内酯的协同作用形成,证实了中药功效理论与现代药理的靶点理论的相关性。