Ultrastructure changes in substantia nigra and striatum after chronic ischemia have an effects on behavior of stereotypy and change function of dopamine system in rats. 慢性缺血大鼠在阿朴吗啡的作用下,刻板动作行为的积分会明显高于正常对照组,提示黑质和纹状体的多巴胺系统功能受到了干扰。
Previous studies suggest that stereotypy is a result of interaction between genetic predisposition and environmental effects. 前人的研究结果表明,行为规癖的表现是遗传上的倾向性和环境影响共同作用的结果。
Autistic Disorder is a group of complicated behavioral syndromes caused by many factors. The clinical features of it includes of social interaction disorder, language development disorder, narrow interests and stereotypy. 自闭症即孤独症(AutisticDisorder)是由多因素引起的以社会交往障碍、言语发育障碍、兴趣范围狭窄和刻板重复的行为方式为基本临床特征的一组复杂的行为综合征。
Therefore all results suggest that early VAD could influence energy metabolism and cytoskeleton in cortex and hippocampus, influence the glutamate signaling and dopamine signaling, and finally lead to schizophrenia like behaviors in mouse: increased locomotion and increased MK-801 induced stereotypy. 因此我们认为早期VAD可能影响皮层和海马能量代谢和细胞骨架,影响谷氨酸通路和多巴胺通路,从而造成小鼠的类精神分裂症行为(旷场行为增加,MK-801诱导的刻板行为增加)。
These abnormal behaviors reflect some faces of schizophrenia like symptoms: such as hyperactivity of locomotion and increased MK-801 induced stereotypy. 这些行为学的异常反映了某些类似精神分裂症的行为,如旷场行为增加和MK-801诱导的刻板行为增加。