thalassaemia

1. The technology works on mice and men; a team in China recently revealed they had partially succeeded in excising the gene for beta thalassaemia, an inherited blood disorder, from a human embryo.
   这种技术可以用于小鼠和人类；中国的一个科研小组最近透露，他们从一个人类胚胎上切除β-地中海贫血症（一种遗传性血液疾病）基因的操作取得了部分成功。
2. Thalassaemia major requires regular blood transfusions to maintain an adequate supply of haemoglobin and sustain life.
   重型地中海贫血需要定期输血，以保持足够的血红蛋白供应并维持生命。
3. They then modelled the effect a malaria attack would have on both normal children and children with alpha thalassaemia.
   然后他们对疟疾攻击正常儿童和患有alpha型地中海贫血症的儿童的效果建立了模型。
4. Alpha thalassaemia, an inherited condition, is common in many areas of the world where malaria is endemic, particularly Africa and southeast Asia.
   这种称为alpha型地中海贫血症的遗传病在全世界许多疟疾流行的地区常见，特别是非洲和东南亚。
5. Children with a specific type of the condition homozygous alpha thalassaemia are60 per cent less likely to develop SMA when suffering from malaria.
   患有特定类型该病的儿童（纯合型的alpha型地中海贫血症）在患疟疾后出现急性疟疾性贫血的可能性要低60%。
6. Recently, gene therapy has been successfully applied to a patient with thalassaemia.
   最近，对一名地中海贫血患者成功地应用了基因疗法。
7. There are two major types of thalassaemia, alpha and beta, which are named for the two protein chains that make up normal haemoglobin.
   地中海贫血主要分为两种，即alpha型和beta型，以组成正常血红蛋白的两条蛋白链命名。
8. This showed that children with homozygous alpha thalassaemia have to lose more red blood cells than their normal counterparts to get SMA.
   模型显示患有纯合型alpha型地中海贫血症的儿童需要失去比正常儿童更多的红细胞才能患上急性疟疾性贫血。
9. NOTE: Anaemia is not always caused by iron deficiency-lead poisoning and thalassaemia can also produce anaemia.
   注意：贫血并不总是由缺铁引起，铅中毒和地中海贫血症也会导致贫血。
10. It is also needed for regular transfusions for people with conditions such as thalassaemia and sickle cell disease and is used to make products such as clotting factors for people with haemophilia.
    地中海贫血和镰状细胞病等病症患者还需要定期输血，并且血液被用于制造各种制品，例如供血友病患者使用的凝血因子。
11. Alpha and beta thalassaemia have both mild and severe forms.
    alpha型和beta型地中海贫血有轻度和重度两种形式。
12. Some people which red-cell mutations such as thalassaemia and sickle cell anaemia inherit an immunity to malaria.
    有些红细胞突变的人，如地中海式贫血痫人和镰状红细胞贫血病人遗传对疟疾的免疫。
13. Application of reverse dot blot hybridization on monitoring the engraftment status after allogeneic hematopoietic stem cell transplantation in thalassaemia
    反向点杂交法监测β-地中海贫血异基因造血干细胞移植后植入状态
14. The Molecular Basis of β-thalassaemia Intermedia in Southern China: Genotypic Heterogeneity and Phenotypic Diversity
    华南地区中间型β地中海贫血的分子基础：遗传异质性和表型多样性
15. Sickle-cell disease and severe forms of thalassaemia ( thalassaemia major) can occur only when both parents are carriers of trait genes for the particular condition.
    只有当父母双方都携带特定疾病的特征基因时，才有可能发生镰状细胞病和严重的地中海贫血（重型地中海贫血）。
16. The Gene of Alpha-Thalassaemia in Chongqing
    重庆地区α地中海贫血基因型研究
17. The Prenatal Gene Diagnoses of β-thalassaemia by PCR-dot-blotting
    应用PCR－斑点杂交方法进行β地中海贫血产前基因诊断
18. A Mossbauer study of thalassaemia
    地中海贫血的穆斯堡尔研究
19. Conclusions: Our study obtained the prevalence and spectrum of α-and β-thalassaemia in Guangzhou Haizhu district. Our results could provide valuable genetic data for genetic counseling, prenatal diagnosis and carrying out population prevention program of thalassemia.
    结论本研究获得了广州市海珠区人群的地贫发生率和基因突变谱的分布特点，为我区开展地贫人群遗传咨询、产前诊断和预防计划提供了有价值的资料。
20. Axonal sensorimotor neuropathy in patients with β-thalassaemia
    β-地中海贫血患者的轴突感觉运动神经病变
21. A Review of Screening and outcome of Thalassaemia Trait in Pregnant Women
    妊娠合并轻型地中海贫血的筛查及妊娠结局的回顾性分析
22. Conclusions Premarital counseling and antenatal diagnosis are important measures to decrease the birth-rate of children with both thalassaemia and G6PD deficiency.
    婚前检查及产前诊断对减少地中海贫血合并G6PD缺乏症患儿的出生具有十分重要的意义。
23. Objective To investigate the single nucleotide polymorphisms ( SNP) of beta-globin gene in beta-thalassaemia carrier. Clinical study of hydroxyurea for the treatment of severe beta-thalassaemia
    目的对临床诊断为轻型β-珠蛋白生成障碍性贫血患者进行β-珠蛋白基因单核苷酸多态性分析。羟基脲治疗重型β地中海贫血
24. PCR-dot-blotting was proved accurate and reliable, and especially applies to the prenatal gene diagnoses of β-thalassaemia.
    PCR－dot－blotting方法准确可靠，尤其适合于β地中海贫血的产前诊断。
25. 3 lymphocytes were picked up from blood samples of 1 healthy female and 4 patients with known β-thalassaemia mutations respectively.
    使用显微操作法分别从1例正常女性及4例β地中海贫血血标本中获得3个淋巴细胞。
26. Objective To study the beta globin gene variability in the beta thalassaemia with glucose 6 phosphate dehydrogenase deficiency patients.
    目的了解β地中海贫血合并G6PD缺乏症患儿的异常β珠蛋白基因突变情况。
27. Mean Corpuscular Volume and Red Blood Cell in the Screening of Thalassaemia Trait in Pregnant Women
    平均红细胞体积和红细胞计数筛查妊娠合并轻型地中海贫血的价值
28. Objectives: To evaluate the value of combined measurement of mean corpuscular volume ( MCV) and red blood cell ( RBC) in the screening of thalassaemia trait in pregnant women.
    目的：探讨平均红细胞体积（MCV）、红细胞计数（RBC）检测在筛查妊娠合并轻型地中海贫血中的价值。

noun

1. an inherited form of anemia caused by faulty synthesis of hemoglobin

   Synonym:    thalassemiaMediterranean anemiaMediterranean anaemia