In general, the sulfonylureas, thiazolidinediones, and D-phenylalanine derivatives have been shown to promote weight gain. 总体而言,磺脲类,噻唑烷二酮类以及苯丙氨酸派生物被证实可促进对体重的增加。
About half were given Actos, a member of a relatively new class of antidiabetic agents known as thiazolidinediones. 约一半给予艾可拓,一种新型的抗糖尿病药物,噻唑烷二酮类。
Protective effect of thiazolidinediones on the kidney 噻唑烷二酮类药物对肾脏的保护作用
A new study has revealed that postmenopausal women with diabetes taking thiazolidinediones ( TZDS), including rosiglitazone and pioglitazone, may be at increased risk for fractures. 一项新的研究显示患有糖尿病的绝经妇女在服用噻唑烷二酮类药物,包括匹格列酮与罗格列酮时,会增加骨折的危险。
The Clinical Value of Thiazolidinediones in Type 1 Diabetes 噻唑烷二酮类药物在1型糖尿病治疗中的价值
Thiazolidinediones Improving the Insulin Resistance in Women with PCOS 噻唑烷二酮类药物改善多囊卵巢综合征患者胰岛素抵抗的作用
Besides being antidiabetic drugs, thiazolidinediones also have positive effects on other diseases, such as cardiovascular disease, inflammation, psoriasis, tumors, etc. 噻唑烷二酮类药物的生理效应和作用机制是医药界的研究热点之一。
Both drugs are so-called thiazolidinediones that were designed to make the body more sensitive to insulin, a hormone the body needs to convert sugar into energy. 这两种药物也共同称作噻唑烷二酮类药物,它们使机体对胰岛素更敏感,胰岛素是一种机体必需的转化糖为能量的激素。
It is also the target molecule of the thiazolidinediones. 它也是糖尿病治疗药物噻唑烷二酮类化合物(TZDs)作用的靶分子。
Advance in the Clinic Use of Thiazolidinediones 噻唑烷二酮类药物临床应用进展
Other potential drugs including advanced glycosylation end product inhibitors, thiazolidinediones, statins are also discussed. 晚期糖基化终末产物抑制剂、噻唑烷二酮类、他汀类药物对糖尿病视网膜病变的治疗也有一定作用。
With the deep research of mechanism of action of thiazolidinediones ( TZDs) which are able to improve insulin sensitivity, people found that PPAR γ is the main functional factor of these drugs. 随着对胰岛素增敏剂噻唑烷二酮(TZD)类药物作用机制的深入研究,发现PARγ是该类药物的主要功能受体。
Conclusions: Thiazolidinediones ( TZDs) rosiglitazone can improve the impaired endothelial progenitor cells in diabetic patients. 结论:噻唑烷二酮类药物罗格列酮对糖尿病患者体内受损的内皮祖细胞的具有改善作用。