All antibodies belongs to IgG1 subclass. Results of toxin-antitoxin neutralization show that 12 out of 13 monoclonal antibodies have the activity of neutralizing e-toxin. 13株单克隆抗体均为IgG1亚类,经毒素抗毒素中和试验测定,13株单克隆抗体中,12株具有中和ε毒素的活性。
We found that more than 300 genes changed, and we selected a pair of toxin-antitoxin genes ( VCA0391/ 2) to investigate whether they can help Vibrio cholerae to escape from death under the bad condition 我们发现超过300个基因均发生了改变,同时我们选取了一对toxin-antitoxin基因(VCA0391/2)进行研究,观察其是否能够帮助霍乱弧菌在恶劣条件下逃避死亡
Toxin-antitoxin gene systems ( TA systems), widely distributed on the chromosome of free-living bacteria, are assumed to be involved in or mediate cell growth inhibition or cell death as a prokaryotic cell stress factor. 毒素-抗毒素系统基因广泛存在于细菌染色体上,可能作为原核细胞的胁迫反应因子,参与或介导中度胁迫条件下细胞的生长抑制或死亡。