HPLC method was established for the determination of the trans-isomer and R-isomer of mitiglinide calcium. 建立了HPLC法测定米格列奈钙的反式异构体和R-异构体。
Among them, the physiologically active of trans-isomer is stronger than the cis-isomer, the monomer activity greater than the glucoside. 其中,反式异构体生理活性强于顺式异构体,单体的活性大于糖苷。