We wanted to make our new similarity measure insensitive to minor mix-ups such as translocations, which represent only a small loss of informational similarity. 我们的新方法必须容忍微小的混乱,例如基因转位,使这类混乱只代表资讯相似度的微小损失。
The32 major anomalies consisted of19 reciprocal translocations, 9 Robertsonian translocations, one large inversion, two triple-X females, and one Turner mosaicism. 在32个主要异常包括19染色体号相互易位,9号染色体罗伯逊易位,一个大的倒位,两个三条X染色体的女性,和一个特纳嵌合体。
Inversion heterozygotes are semi-sterile. Certain autosomal translocations in the heterozygous state can be fully viable. 易位杂合体是半不育的。呈杂合子状态的某些常染色体易位完全可以生活的。
Chromosome breaks may also lead to inversions and translocations. 染色体破裂也可能引起倒位与易位。
Preimplantation genetic testing for chromosomal translocations is able to distinguish between chromosomally normal and abnormal embryos. 染色体易位植入前基因检测能够区分正常和异常染色体的胚胎。
Research of Expression and Clinical Significance of Genes Associated with Common Ig Translocations in Multiple Myeloma 多发性骨髓瘤常见免疫球蛋白易位相关基因的表达及临床意义研究
Translocations can affect the ALK gene resulting in the expression of oncogenic fusion proteins. 易位可以影响ALK基因在致癌融合蛋白的表达。
Genetic damage with DNA alterations leads to point mutations of genes, translocations of genetic material between chromosomes, and gene reduplication with amplification. 伴随DNA改变的基因损伤会导致基因的点突变、染色体间基因移位和扩增性基因复制。
FISH studies of deletion of derivative chromosome 9 in chronic myeloid leukemia patients with variant philadelphia translocations 变异型Ph易位慢性粒细胞白血病der(9)缺失的FISH研究
Obvious karyotypic differentiation among the populations, which was highlighted by chromosomal aberrations, including mainly pericentric inversion and the Robertsonian or unequal reciprocal translocations, was detected. 种内的核型分化与染色体的结构变异有关。主要表现为臂间倒位、罗伯逊易位和或不等相互易位。
His father was a carrier of two apparently unrelated balanced reciprocal translocations, but his phenotype was normal. 其父为罕见的2对平衡易位携带者,但表型正常。
Intermedium. Besides, two possible spontaneous translocations were found in two alien addition lines, TAI-14t and TAI-27s. 此外还发现在其中的两个异附加系(TAI-14t和TAl-27s)中可能产生了自发易位。
There were 473 pregnancies in 130 carriers of balanced translocations; their spontaneous abortions rate was 90.1%. 130例平衡易位携带者共有473次妊娠,流产占90.1%,死胎、分娩异常后代、分娩正常后代、分娩易位后代分别为4.7%、4.0%、1.1%、0.2%。
Meiotic segregation results of male reciprocal chromosome translocations 精子荧光原位杂交分析男性染色体相互易位携带者的减数分裂分离
In this paper we report a case of a chromosome structural aberration with three reciprocal translocations involving six chromosomes. 本文报道了一例极为罕见的、涉及六条染色体有三个易位的染色体结构畸变。
The role of chromosome interchanges, loss of heterochromatin, alien chromosome substitutions and translocations and other variations in chromosome structure in the karyotypic evolution of common wheat and hexaploid triticale will be evaluated in this paper. 本文从染色体相互易位、异染色质的丢失和外源染色质的导入三个主要方面讨论普通小麦和六倍体小黑麦核型的变化情况。
Using Chinese hamsters heterozygous for T ( 2; 10) 3Idr and T ( 1; 3) 8Idr reciprocal translocations, the authors studied mitomycin C ( MMC)-induced crossing-over on the interstitial segments. 本文用MMC对T(2;10)3Idr和T(1;3)8Idr相互易位雄性杂合中国仓鼠诱发减数分裂过程中间节段交换进行了研究。
Translocations of boron in cotton were different in different period of growth. 棉花叶片对硼的运输随棉花生长时期不同而异:营养生长时期,硼主要运输到生长点和幼嫩叶片中;
C banding reveals the three translocation lines are 1BL/ 1RS translocations. C-分带表明3个受检易位系为1BL/1RS易位。
In this paper, alien chromosome arms and its fragment length involving in 13 alien translocations were determined. 同时还对13个普通小麦&大赖草易位系进行了SSR分析,初步确定了易位涉及到的外源染色体臂、易位片段的大小以及可用来追踪这些易位染色体的SSR标记。
Some rye chromosome arms were observed more frequently than the others in translocations. 不同的黑麦染色体臂参与易位的频率不同。
A study on small segments and complicated chromosome translocations with fluorescence in situ hybridization 染色体荧光原位杂交技术研究小片段和复杂的染色体易位
The genomic sorting problem is to find a minimum length sequence of rearrangements ( reversals or translocations) by which source genome can be transformed into target genome. 寻找一个基因组(源基因组)转化成另一个基因组(目标基因组)所需最少数目移位和翻转的问题,称为基因组重组问题.此问题的瓶颈在于寻找源基因组的一个最优联接;
By molecular detection, we can get chromosomes C-banding and small segments translocations which were not detected by hybridization in situ, and some of the small segments translocations have more meaningful in variety improvement. 利用分子检测,可以得到染色体C-分带与原位杂交检测不到的小片段易位,而这种小片段易位有的在品种改良上更有意义。
Non-random chromosomal translocations, hematopoiesis-related oncogenes or antioncogenes mutations are the important pathogenesises of human leukemia, as well as disorders of hematopoietic transcription factors or cytokine network can promote the development of leukemia. 非随机染色体易位、造血相关的原癌基因或抑癌基因突变是人类白血病的重要发病机制之一,造血相关的转录因子、细胞因子网络异常可以促进白血病的发展进程。
If a genome can be transformed into another only by reciprocal translocations, the two genomes must have the same set of chromosome ends. 一个基因组若仅通过交互型移位转化为另一个基因组,那么这两个基因组必须具有相同的尾基因集合。