At present, we consider NO released by activated macrophages can kill target cells by restraining the tricarboxylic acid cycle, electron transfer and composition of DNA in target cells. 目前认为,经激活的巨噬细胞释放的NO可以通过抑制靶细胞线粒体中三羧酸循环、电子传递和细胞DNA合成等途径,发挥杀伤靶细胞的效应。
In this way, tracers used to study amino acid uptake, protein synthesis, DNA synthesis, cell proliferation, changes of other substrates of tricarboxylic aciol cycle metabolism, tumor hypoxia, immunological activity and receptor are expected to be new tumor imaging agent. 因此,其他一些用于研究氨基酸摄取、蛋白质合成、DNA合成、细胞增殖、三羧酸循环中其他底物的代谢改变、肿瘤乏氧性、免疫活性和受体的示踪剂有望成为新的肿瘤显像剂。
Orthogonal design was adopted to show the influences of ratio of reactants, reaction temperature, amount of catalyst, reaction time on the synthesis of C_ ( 22)-methyl diisoamyl esters of tricarboxylic acid. 采用正交实验设计探讨了C22-三元酸的甲基二异戊酯的投料比、温度、催化剂用量、反应时间对合成反应的影响。
MtDNA mutation result in insulin deficiency by tricarboxylic acid cycle ( TCA cycle) obstruction. 线粒体基因突变可通过三羧酸循环障碍导致β细胞分泌胰岛素不足。
The triesters of C_ ( 22)-tricarboxylic acid could be prepared by the Diels-Alder adduct using methyl ester of cottonseed oil as raw material, change non-conjugated methyl linoleate into conjugated methyl in the presence of catalyst, then react with diesters of fumarate. C22-三元酸三酯的合成以棉籽油甲酯为原料,将非共轭的亚油酸甲酯在催化剂作用下转化成共轭亚油酸甲酯,同时与富马酸二酯发生Diels-Alder反应,生成C22-三元酸三酯。
Study on c_ ( 22) tricarboxylic triglycidyl ether type epoxy resin C(22)三羧酸三缩水甘油酯型环氧树脂的研究
Synthesis of C_ ( 22)-triesters of tricarboxylic acid C(22)-三元酸三酯的合成
Tricarboxylic acid ( TCA) cycle is an important way to generate ATP, which is widely distributed in the cells of animal, plant or microorganism. 在动物、植物、微生物细胞中普遍存在的三羧酸循环(TCA循环)是产生ATP的主要途径,它不仅参与糖的分解代谢,也参与蛋白质和脂肪的分解代谢。
Research on the synthesis of c_ ( 22) dicarboxylic acids and c_ ( 22) tricarboxylic acids from oils 油脂合成C(22)二元酸及三元酸的研究
Crosslinking of Cotton Fabric with Tricarboxylic Acid 棉织物三羧酸酯化交联整理研究
The results showed that the efficiency of 2 phosphinic acid tetrane 1,2,4 tricarboxylic acid ( PBTCA) was better than that of the hydroxyl ethylidene bis ( 2 ethylhexyl) phosphoric acid ( HEDP) and the polybasic alcohol phosphonate ester ( PC 604). 结果表明,阻垢剂2膦酸丁烷1,2,4三羧酸(PBTCA)明显优于多元醇膦酸酯(PC604)和羟基乙叉二膦酸(HEDP),HEDP与PBTCA复配明显优于与PC604复配。
Moreover, Amino acid, as a tricarboxylic acid cycle substate, has been proved to be able reduce impairment of reperfusion in infant myocardium protection. 另外氨基酸作为心肌有氧代谢的三羧酸循环底物,在婴幼儿心肌保护中因能明显减轻缺血、缺氧心肌的再灌注损伤而日益受到重视。
C_ ( 22)-Tricarboxylic acid was synthesized from the fatty acid of cottonseed oil by converting non-conjugated linoleic acid to conjugated linoleic acid in the presence of iodine as catalyst, followed by Diels-Alder reaction between conjugated linoleic acid and fumaric acid. 以棉籽油脂肪酸为原料,将非共轭的亚油酸在碘催化下转化成共轭亚油酸,同时与富马酸发生Diels-Alder反应,制备了C(22)-三元酸。
Acetyl CoA into the tricarboxylic acid cycle provides energy for metabolism of organisms. 然后乙酰辅酶A再进入三羧酸循环为生物体新陈代谢提供能源。
All above described changes of the metabolic components indicated that restraint stress led to glycolysis 、 gluconeogenesis capacity 、 tricarboxylic acid cycle as well as the disorder of lipid metabolism disordered. 这些代谢成分的改变提示束缚应激可导致能量代谢中糖酵解、糖异生能力、三羧酸循环的改变以及肝脏脂代谢的紊乱。
In addition, about half of the enzymes and coenzymes in the tricarboxylic acid cycle contain iron or need the presence of iron. 此外,参加三羧酸循环的酶和辅酶约半数含有铁或需要铁的存在。
Malate dehydrogenase ( MDH) is the key enzyme of tricarboxylic acid cycle ( TCA), which is commonly observed in living organisms. 苹果酸脱氢酶(MDH)是三羧酸循环中的一个关键酶,在生物体内普遍存在,MDH以NADH或NAD+为辅因子,催化苹果酸盐与草酰乙酸盐的相互转化。
The increased recent studies in vitro have showed that Al ( III) could inhibit the activity of enzyme which catalyzed the tricarboxylic acid cycle ( TCA) and glycolytic cycle, thereby the production of energy generated by mitochondrial cell was badly affected. 越来越多的体外研究表明,铝能够抑制三羧酸循环和糖酵解过程中酶的活性,因此线粒体细胞供能系统受到严重的阻碍。