This phenomenon is mostly seen in imprinted genes and X-chromosome inactivation where DNA methylation of promoter regions leads to repression of gene expression. 这种现象主要在印迹基因和X染色体失活区域看到,这些区域中的启动子区的DNA甲基化导致了基因表达的抑制。
The patient ′ s mother was the carrier of the heterozygosis mutation in X-chromosome. 患儿母亲为X染色体突变基因杂合子携带者。
Because these genes are carried on the X-chromosome, they are subject to a process known as X-chromosome inactivation. 由于这些基因存在于X染色体上,它们发生了X染色体失活的处理。
To assess the clonal origin of renal clear cell carcinomas by the study of X-chromosome inactivation pattern in female clear cell renal carcinomas and normal renal tissues. 本实验将通过研究女性肾透明细胞癌及正常肾组织的X染色体失活类型判断肾透明细胞癌克隆起源。
The Application of STRs of X-chromosome and Autochromosome in Duo-cases X-STR和常染色体STR在二联体亲权鉴定中的应用
As mentioned above, the X-chromosome contains the genes associated with reproduction, mental function, skeletal muscle and a part of skeleton characteristic. 上述所说的,X染色体包含了基因所关联的生殖,智力,骨骼肌,和一部分的骨骼性状。
The x-chromosome has many genes for which there are no paired genes on the Y-chromosome. x染色体有许多在Y染色体上不能配对的基因。
Clonal Origin Study of Clear Cell Renal Carcinoma by X-chromosome Inactivation Pattern 肾透明细胞癌克隆起源的X染色体失活类型研究
The microRNAs have the effect of "silencing" immunity genes on X-chromosome, according to the new research. 根据这项新研究,微RNA具有“遮罩”X染色上的免疫基因的效果。
If a Y-chromosome combines with an X-chromosome during fertilization, a male baby will result. 若一个y染色体在授精过程中与一个x染色体结合,就会产生一个男婴。
In mammals, every cell in females has two X-chromosomes, while every cell in males has a single X-chromosome. 在哺乳动物中,每一个雌性细胞有两条X染色体,而每一个雄性细胞有一条X染色体。
Objective: To study the application of specific genetic pattern of X-chromosome STR loci in siblings'identification. 目的:探讨X染色体STR基因座独特的遗传方式在同胞亲缘关系鉴定中的应用。
Loss of X-chromosome inactivation mosaicism was observed in all the 321 tumor nodules examined from 77 cases, reflecting their clonal cellular composition. 对适合于检测的77例共321个瘤结节进行了检测,所有瘤结节均表现为X染色体失活嵌合性丢失,是单克隆性的;
The Behavior of X-Chromosome During Differentiation of Female Teratocarcinoma Cells in vitro 雌性畸胎瘤细胞离体分化时X染色体的行为
Random inactivation of one X-chromosome in somatic cells offers a probability for the clonality analysis. X染色体随机失活类型的分析不但为克隆性分析提供了可能性,而且可以显示同一疾病不同个体的易感性。
Prenatal diagnosis of X-linked anhidrotic ectodermal dysplasia with X-chromosome inversion X染色体倒位伴X连锁无汗性外胚叶发育不良一个家系的产前诊断
X-chromosome inactivation patterns of different tumor nodules in multiple leiomyomas of uterus 子宫平滑肌瘤不同结节X染色体失活类型的研究
This article summarizes the structure and hereditary characteristics of X chromosome, research progress of using multiplex PCR system to amplify X-chromosome specific short tandom repeat ( X-STR) loci and its forensic applications. 对X染色体的结构特征、遗传特征等相关基础知识及其短串联重复序列(STR)基因座在法医学领域的研究历史、现状,复合扩增的研究动态和应用等方面进行了综述。
To study the relations between X-ray and the frequency of micronuclei with X-chromosome, the occurrence of Chromosome 7 and X chromosome within micronuclei induced by Xrays wa. s simultaneously scored in binucleated human lymphocytes using whole chromosome painting technique. 为了研究X射线与X染色体的微校率之间的关系.本实验利用原位杂交技术同时检测了经X射线诱发人双核淋巴细胞的7号和X染色体的微核率。
Methods: From Oct, 2002 to Dec, 2004,204 children with different degree MR, X-chromosome fragile site were detected by low folic acid cultivation. 方法:对2002年10月-2004年12月该院门诊和病房不同程度的智力低下病人204例进行了外周血淋巴细胞低叶酸培养方法诱导脆性位点脆性X染色体研究。
Role of clonality analysis by X-chromosome inactivation in the diagnosis of cervical lymph node occult micrometastasis from squamous carcinoma of the head and neck X染色体灭活方式检测在诊断头颈鳞状细胞癌颈淋巴微转移中的作用
The Inter-nodular Relationship in Multiple Leiomyomas of the Uterus Demonstrated by X-chromosome Inactivation Patterns 根据X染色体失活类型探讨多发性子宫平滑肌瘤不同结节之间的关系
X-chromosome typing and sex determination X染色体与性别鉴定
Trisomy of the short arm of chromosome 9 ( 9p+) and distal deletion of the long arm of X-chromosome were found with G banding and C-banding techniques. 用G带和C带技术鉴定为第9号染色体短臂三体(9p+)和一条X染色体长臂远端部分缺失(xq&)。
Histone lysine methylation has important functions in many biological processes that include gene expression, X-chromosome inactivation, gene imprinting and DNA repair. 组蛋白赖氨酸甲基化作为共价修饰的一种在基因表达调控、X染色体失活、基因组印迹、DNA修补等生物学过程中起重要作用。
DNA methylation regulates critical biological phenomena such as X-chromosome inactivation, genomic imprinting, chromatin structure and regulation of gene expression. What is more, it has been shown to be essential for cell differentiation and embryo development. DNA甲基化调控着重要的生物学现象,比如X染色体的失活、遗传印记、染色质结构以及基因表达,并且在细胞分化和胚胎发育过程中也起着极其重要的作用。