xist

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网络 X染色体失活基因

Molecular Mechanism of X-chromosome Inactivation Mediated By Non-coding RNA Xist
非编码RNAXist调节X染色体失活的分子机制
Recently it has been proposed that an X remains active when certain proteins aggregate at a specific spot on the chromosome, shutting down its "suicide gene" XIST.
近来有人提出当某种蛋白质聚集在一个X染色体特定部位时，这条染色体将保持活跃，并抑制其“自杀基因”XIST。
The Transcription Pattern of Xist in the Development of Mouse Preimplantation Embryo
小鼠胚胎早期发育过程中Xist基因的转录模式
These results suggest that the DNA methylations of the Xist gene were reprogrammable and the detected CpG islands may regulate expression of the Xist gene.
这些结果说明，Xist基因DNA甲基化是可以被重编程的，所检测的CpG岛可能调节Xist基因的表达。
The XIST gene maps to the XIC region on the mouse and human X chromosome and is thought to be involved in the initiation of inactivation, making it a strong candidate for XIC itself.
XIST基因定位于XIC中，参与X失活的启动，可能是X失活决定基因。
After long-term culture, epigenetic status of these cells changed, XIST gene expression could be detected accompanied by the occurrence of XCI. 6.
长期培养后，伴随XCI的发生，XIST基因表达可检出。
No expression of XIST gene was detected at early passages.
XIST基因在早期不表达。