But I think it could influence the decision making of women who are deciding whether to take a bisphosphonate or not. 但是我认为它能影响女性是否服用双磷酸盐类的决定。
Aliquots of phosphate buffered saline were administered in the same protocol without bisphosphonate in the control group. 对照组按同样的方式给予等量的生理盐水。
Ibandronate, a nitrogen-containing bisphosphonate, has been used for the treatment of metastatic bone disease and skeletal complications of bone metastases. 伊班膦酸钠为三代含氮双磷酸盐,已被临床应用于治疗恶性肿瘤骨转移及继发的骨相关事件。
Bisphosphonate have bone? seeking affinity, some of them are used as drugs for osteoporosis. Imaging Findings of Bisphosphonate-associated Osteonecrosis of the Jaws 双膦酸盐有趋骨性并有抗骨质疏松症活性。二膦酸盐相关性颌骨骨质坏死的影像学表现
Results By3 weeks when bisphosphonate started to be administered, woven bones formed in the periphery of the BMP pellets. 结果:BMP诱导骨3周时(即双膦酸盐未投药前),在BMP植入体周边形成编织骨,大量破骨细胞出现在新生骨组织表面。
This article reviews the recent evidences on the risks and benefits of bisphosphonate therapy for many different cancers, especially its role in the management of skeletal metastases. 本文回顾了双膦酸盐在多种恶性肿瘤骨转移中的临床研究结果及安全性。
Conclusion These findings suggest that bone resorption can be inhibited by the bisphosphonate. 结论:双膦酸盐对骨形成蛋白诱导骨破骨骨吸收有明显的抑制作用。
Across all studies, no clear association between overall bisphosphonate exposure and the rate of serious or non-serious atrial fibrillation was observed. FDA认为,这些研究尚不足以断定双磷酸盐药物与严重或不严重的房颤发生率之间存在明显的相关性。
Bisphosphonate medicines are a common treatment that can be used to slow the effects of the condition. 二膦酸盐药物,是一种常见的治疗可以用来缓慢的影响条件。
There was no significant increase in risk associated with bisphosphonate use, but the study was underpowered for definitive conclusions. 没有与双膦酸盐使用相关的危险显著增加,但本研究没有足够的效能得出肯定的结论。
We developed a simulation of adherence to bisphosphonate therapy in the US. 在美国我们制订了一套坚持服用二磷酸盐的治疗方案。
Conclusion: In groups of patients, short-term changes in markers of bone turnover appear to be predictors of longer term BMD response and nonresponse to bisphosphonate therapy. 结论:短期内骨转化标志物的变化可以预测患者骨密度对双磷酸盐治疗的远期反应。
Bisphosphonate have bone? Seeking affinity, some of them are used as drugs for osteoporosis. 双膦酸盐有趋骨性并有抗骨质疏松症活性。
Four cases had suffered from new fragile fracture in bisphosphonate group ( 2 cases), HRT group ( 1 case) and calcitonin group ( 1 case). 新骨折共4例:二膦酸盐组2例,降钙素组和性激素组各1例;
Objective To observe the changes of urinary deoxypyridinoline crosslink/ creatinine ( UDpd/ Cr) in rats after OVX and intervention by estrogen and bisphosphonate and investigate the possible application of deoxypyridinoline in osteoporosis diagnosis and treatment. 目的观察大鼠去卵巢及予以不同的干预后尿脱氧吡啶啉/肌酐比率(urinarydeoxypyridinolinecrosslink/creatinine,UDpd/Cr)的变化,了解其在骨质疏松的诊断和治疗中的应用价值。
Long-term bisphosphonate administration increase the degree of mineralization in bone 双膦酸盐的长期治疗增加了骨单位的矿化程度
In drug treatment, calcitonin, bisphosphonate ( alendronate), HRT ( Livial), vitamins D2 and D3, and calcium are indicated. 在药物治疗方面,降钙素、激素替代疗法(利维爱等)、双磷酸盐(福善美等)、维生素D2、维生素D3及钙剂都是适用的。
Conclusions Long-term bisphosphonate administration in higher dose significantly suppresses bone turnover, which increases the degree of mineralization in bone. 结论双膦酸盐长期应用明显抑制了骨转换,增加了骨单位的矿化程度。
A study of the effects of bisphosphonate on aseptic loosening of prothesis in vitro 二磷酸盐对人工关节松动影响的实验研究
Conclusions Osteoclast-mediated bone resorption was inhibited by the bisphosphonate administration. 结论双膦酸盐对破骨细胞性骨吸收有明显的抑制作用。
Objective: To investigate the effects of bisphosphonate ( BP), an inhibitor of bone resorption, on the remodeling of the rat palatal suture after rapid expansion. 目的:研究二磷酸盐(BP,一种骨吸收抑制剂),对大鼠快速上颌扩弓后腭中缝骨质重建的影响。
Effects of bisphosphonate on ectopic bone induced by bone morphogenetic protein 双膦酸盐对骨形成蛋白诱导骨的作用
Peritoneal macrophages were depleted by the intraperitoneal injection of liposome encapsulated disodium dichloromethylene bisphosphonate ( liposome-CL2MBP). 间歇腹腔注射包裹了氯屈磷酸二钠的脂质体耗竭腹腔巨噬细胞。
Nowadays, the therapy of this disease limited to gastrointestinal tolerance and high expenses, ties in bone-invigorating therapeusis and administration of calcitonin, fluoridizer and bisphosphonate. 目前治疗本病主要在于健骨治疗及降钙素、氟化剂、二膦酸盐药的使用等,并受限于胃肠道耐受情况及高昂的费用。
Risedronate sodium, a third-generation bisphosphonate with pyridyl, is the earliest protein inhibitor of bone absorption on market and its effect was stronger than earlier the first and second-generation products. 利塞膦酸钠为第三代双膦酸盐类抗骨质疏松药物中上市较早,疗效明显的强于一、二代产品。